Croatia is let down

Apoptotic cells let down their guard

Unfolding chromatin nets Spiderman doesn’t have anything on neutrophils, which snag microscopic bad guys with webs of chromatin. Wang et al. show that by unfurling chromatin, a histone-modifying protein helps the defensive cells set their traps. During an infection or infl ammation, dying neutrophils spill their DNA to form pathogentrapping NETs (neutrophil extracellular traps). This gooey mate...

Alpaca fiber growth is mediated by microRNA let-7b via down-regulation of target gene FGF5.

MicroRNAs are very small endogenous RNA molecules that play a crucial role in an array of biological processes, including regulation of skin morphogenesis. The microRNA let-7b is thought to modulate animal hair growth, by binding target genes that encode growth factors. Fibroblast growth factor 5 (FGF5) has been previously reported to be involved in the initiation of the catagen phase of hair g...

Delayed Lead Perforation: Can We Ever Let the Guard Down?

Lead perforation is a major complication of cardiac rhythm management devices (CRMD), occurring in about 1%. While most lead perforations occur early, numerous instances of delayed lead perforation (occurring >30 days after implantation) have been reported in the last few years. Only about 40 such cases have been published, with the majority occurring <1 year after implantation. Herein, we desc...

DDT is back: let us spray!

Inhibition of oxytocin release and milk let-down in postpartum primiparous cows is not abolished by naloxone.

About 10% of primiparous cows have no milk ejection during the first milkings after delivery. Therefore, 17 Brown Swiss dairy cows in their first lactation were used to evaluate the extent of disturbed milk let-down and the corresponding oxytocin (OT) plasma values in the 1st 5 days after delivery. The first milking was 9-22 h after parturition and served for classification of the cows to group...